From Kathy Ruffing at the Center for Budget and Policy Priorities:
Labor-force participation — the share of adults 16 and older who are working or looking for work — peaked at just over 67 percent in 1996-2000 and has fallen since then. Some analysts observe that the number of Social Security Disability Insurance (SSDI) beneficiaries grew steeply after 2000, and assume the two trends are related. But evidence for that connection is weak. ...
I'd call that chart a definitive answer to the question.
Rising SSDI receipt and falling labor-force participation aren’t affecting the same age groups. SSDI receipt has grown modestly among older people, especially older women (see graph) — but so has their labor-force participation, as older workers postpone retirement. The drop in labor-market activity is concentrated at younger ages, particularly men, where SSDI receipt has not risen.